Fenticonazole Nitrate - A Symptomatic Approach to Vulvovaginal Infection
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چکیده
Fenticonazole shows unique multimodal action against Candida species involving: 1. Inhibition of secretary aspartate protenase (SAP) there by preventing the growth, adherence, and penetration of Candida sp. including N-acetylcysteine leading to clinically significant reduction in the relapse rate (Figure 1). 2. Inhibits fungal cytochrome P450 3A enzyme, lanosine 14α-demethylase responsible for conversion of lanosterol to ergosterol, the main sterol attributed to fungal cell membrane integrity and cell survival. INTRODUCTION
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تاریخ انتشار 2017